Space Explorer

Get insights into the spatial gene expression and phnotypes of IHD.

SHOW DEG SHOW CellType SHOW Deconvolution SHOW Program

Control panel

Embedding:
space UMAP
Show cell types:
Expr. plot:
Load more DEGs:
Module plot:
Cell type plot:
Download top 100 enriched pathways of each module:
P1 P2 P3 P4 P5 P6 P7 P8 P9 P10 P11 P12 P13 P14 P15 P16 P17 P18 P19 P20 P21 P22 P23 P24 P25 P26 P27 P28 P29 P30
Sender-receptor pair:
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Show CCI heatmap:
Selected spots will show here.
Not saved unless set as groups!
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Tips:
To construct a DEG network from the DEGs, click the .

Tips:
The axis label of the bubble plot might be hidden when >40 ligand-receptor pairs are presented. In this case, you can zoom in the plot to keep less than 40 L-R pairs to show the label.
The heatmap of all cell type pairs (right bottom) is clickable! This allows switch among all cell type pairs swiftly.

Tips:
The heatmap of pathway enrichment result is clickable! Click a pathway to see the enrichment score of it and its neighboring four pathways.

Tips:
The gene modules were calculated by NMF at a target of 30 dimensions, which could probably cover features of all subclusters. The genes with the top 50 largest power in each module can be viewed on the "Module plot" button.

Tips:
The cell-type scores were calculated by cell2location with our single-cell atlas as reference.

The top three Reactome pathways enriched for are: