Literature
ssIHDB is a public database for ischemic heart disease (IHD) and its clinical complications. This release involves:
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genes/loci supported by literature;
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,
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drugs recorded by DrugBank;
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IHD-related pathways;
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IHD clinical comorbidities;
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tissue categories or cell lines mentioned in IHD literature.
Network tools
ssIHDB provides on-line tools for construction of custom "disease-target-drug" networks from:
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human, mouse, or rat protein-protein interactions;
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,
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miRNA-target interactions;
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drug-target interactions;
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disease-gene relationships;
Annotated differentially expressed genes (DEGs) from single-cell datasets.
Single-cell exploration
ssIHDB selects
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high-quality scRNA-seq samples from
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researches on IHD etiology, which includes:
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,
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,
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single-cell profiles;
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human and mouse major cell types from myocardium, vessels, and plaques;
DEGs of each cell types and samples, cell-cell interactions, enriched canonical pathways, and 30 annotatied gene programs were available for samples.
Spatial exploration
ssIHDB selects
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high-quality spatial transcriptomics (ST) samples
related to IHD, which includes:
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,
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spatial spots profiles;
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spatial domains of myocardium;
DEGs of each spatial domain, cell type deconvolution, spatial mapping, and 30 annotatied gene programs were available for samples.
Report new findings!
The cardiology research community is encouraged to submit their findings to ssIHDB, including
new IHD related genes, comorbidities, and noval studies by means of single-cell and spatial omics.
Update Announcement
Our website is still being updated and may sometimes be unstable.
#866 Yuhangtang Road, Xihu District, Hangzhou, Zhejiang Province, CHINA
College of Pharmaceutical Sciences, Zhejiang University.