Literature

idCHD is a public database for coronary heart disease (CHD) and its clinical complications. This release involves:
6 , 0 3 5 genes/transcripts/loci supported by literature;
3 , 1 5 7 drugs recorded by DrugBank;
4 8 CHD-related pathways;
7 9 CHD clinical comorbidities;
6 0 tissue categories or cell lines mentioned in CHD literature.

Network tools

idCHD provides on-line tools for construction of custom "disease-target-drug" networks from:
1 3 6 , 0 2 0 human, mouse, or rat protein-protein interactions;
1 0 , 0 4 3 miRNA-target interactions;
5 , 6 3 5 drug-target interactions;
2 , 2 7 5 disease-gene relationships;
Annotated differentially expressed genes (DEGs) from single-cell datasets.

Single-cell exploration

idCHD selects 1 6 5 high-quality scRNA-seq samples from 2 2 researches on CHD etiology, which includes:
5 8 5 , 4 1 2 single-cell profiles;
2 9 human and mouse major cell types from myocardium, vessels, and plaques;
DEGs of each cell types and samples, cell-cell interactions, enriched canonical pathways, and 30 annotatied gene programs were available for samples.

Report new findings!

The cardiology research community is encouraged to submit their findings to idCHD, including
new CHD related genes, comorbidities, and noval studies by means of single-cell and spatial omics.

If you want to report your findings, please contact wangth268@zju.edu.cn

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